Thanks OTarchive, just before I posted the last message I was going to delete my sig, as I wasn't sure if it was acceptable, ie too negative or inappropriate, and as there aren't many other sigs to compare it with, it seemed a bit out of place. I tried to go for the balance of 'this is what ails me' but 'this is what I like in life' so thanks muchly for the reassurance and the thumbs up.
Finding any med for neuropathic pain (NeP) has been really difficult, I can put up with some side-effects if the benefits are tangible, but for me they haven't been at all. Just my bad luck I think, as quite a few others I know have had good results with some of these drugs. It's all hit and miss though, some can't tolerate GabaP but pregabalin does the trick, others find the opposite, then there are those for whom it does nothing or too much in the way of side effects.
It appears to be the same with the other meds for NeP, other Anti-seizure meds and various anti-depressants, such as amitryptyline and the newer SSRIs and SNRIs. Opiates or opioids aren't as useless as some Doctors like to make out.
I had success with amitriptyline, it seemed to work very well for my NeP, but sedation, dry mouth, difficulty peeing, and being rather spaced out were troublesome but bearable because of the effectiveness of the pain relief. However, I had to stop taking it due to fairly serious cardiac arrhythmias that it was causing. I had the same problems with other anti-depressants and Tramadol. Just my bad luck again, on paper tramadol appears to be an ideal drug for NeP.
Most NSAIDS and aspirin-a-likes cause too much tinnitus and ear disturbance for someone with meniere's, so I just about bump along the bottom with paracetamol and a prescribed opiate. Not Ideal but it's the best combo for me, when all else is taken into consideration. I eventually got to this point with the help of a Pain Specialist, and I also had some help from physiotherapists along the way, although that can be hit and miss too.
Sorry I've strayed from the Gaba-pregaba thread, looking back on it I'm amazed I tried so many different drugs, and there are still some I would have liked to have tried. But I suppose I've found a point where things are not perfect but stable to a certain extent, and that is quite a relief in itself.